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Most people have heard of coenzyme Q10 (CoQ10), as it often appears in shampoo and cosmetic adverts. However, few know what it actually is or how it works, and even fewer realise how beneficial it is for the human body. While it’s commonly linked to skin health and appearance, its benefits reach far beyond that. That’s why we’ve decided to highlight 5 surprising benefits of CoQ10.
CoQ10 is a powerful compound with strong antioxidant and anti-inflammatory properties. It supports everything from your skin and muscles to your heart and brain. Anyone not using it is missing out. If a lack of knowledge is the only thing stopping you, this article will give you all you need to start taking advantage of what CoQ10 has to offer.
We’ll explain exactly what CoQ10 is, explore its main benefits, and show how it produces each one. By the end, you’ll understand why this compound is so valuable and why it’s worth adding to your daily routine.
Table of Contents
Coenzyme Q10 (CoQ10) is a naturally occurring compound found in every cell of the human body. It’s essential for energy production and provides powerful antioxidant protection for many organs.
Beyond topical products, CoQ10 can be obtained from a wide range of dietary sources. These include organ meats, fatty fish such as mackerel, salmon, and sardines, as well as chicken, pork, and beef. It’s also found in nuts, seeds, and oils like canola, pistachio, sesame, and soybean, and in fruits and vegetables such as broccoli, spinach, and strawberries.
Clinical studies show that CoQ10 works well with nutrients like PQQ (pyrroloquinoline quinone), fish oil, resveratrol, vitamin C, vitamin D, vitamin E, B vitamins (especially B2 and B3), L-carnitine, and selenium. You can also safely combine CoQ10 supplements with topical products that contain it, such as shampoos.
This makes Prime Male S-Volume and Prime Male T-Vitamins excellent CoQ10 supplements, as both include L-carnitine, selenium, vitamin C, vitamin E, vitamin B2, vitamin B3, and several other key B vitamins in their formulas. Prime Male T-Vitamins also contains vitamin D.
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Order NowCoenzyme Q10 supports fat metabolism by enhancing mitochondrial function. This leads to more efficient fat burning and energy conversion, contributing to better metabolic balance, blood sugar control, and energy levels, and may even support weight management (1).
It’s also essential for producing ATP (adenosine triphosphate), the body’s main energy molecule, in the mitochondria. By improving mitochondrial efficiency, CoQ10 helps cells use glucose more effectively for energy instead of storing it as fat, which further improves energy and blood sugar levels (2).
CoQ10 also reduces free radicals, oxidative stress, and inflammation, all of which can impair insulin function. By protecting pancreatic beta cells, which produce insulin, and improving insulin receptor activity, it enhances insulin sensitivity, prevents insulin resistance, and supports better glucose uptake by cells (3).
Since high blood sugar increases free radical production, CoQ10’s antioxidant properties help protect blood vessels, nerves, and tissues from oxidative damage often seen in diabetics while helping to restore normal levels.
Its ability to boost energy and lower inflammation also makes CoQ10 useful for preventing or treating fatigue and supporting longer, more intense physical and sexual activity.
We briefly mentioned Coenzyme Q10’s antioxidant properties above but didn’t fully explore the extent of its protection. Coenzyme Q10 exists in two forms: ubiquinone (oxidised) and ubiquinol (reduced). Ubiquinol provides most of CoQ10’s antioxidant power by donating electrons to neutralise free radicals and prevent them from damaging DNA, proteins, and cell membranes.
It also helps recycle and regenerate other antioxidants, such as vitamins C and E, restoring their activity after they neutralise free radicals and maintaining antioxidant balance. This creates a synergistic defence system within cells that protects them, along with the mitochondria and lipids, from oxidative stress and damage, slowing ageing and the onset of chronic diseases.
The mitochondria are the main site of energy production and the source of reactive oxygen species (ROS). CoQ10 sits within mitochondrial membranes and protects these structures from oxidative stress, preserving energy efficiency and production.
CoQ10 also stabilises and protects cell and lipoprotein membranes, including LDL (“bad”) cholesterol, from oxidation. This helps reduce lipid peroxidation, inflammation, and plaque buildup in arteries. By reducing oxidative damage to DNA and proteins, CoQ10 slows cellular ageing and supports the vitality of key tissues, including the heart, brain, and skin (4).
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Coenzyme Q10 strongly supports every aspect of cardiovascular health. It begins with its anti-inflammatory effects, which neutralise free radicals and reduce inflammatory markers and oxidative stress in the vascular system. This helps maintain flexible arteries, healthy heart cells and tissues, and functional blood vessels while lowering long-term cardiovascular risk.
Because oxidised LDL cholesterol is a major cause of plaque formation, CoQ10’s ability to prevent this oxidation helps reduce artery blockages and the risk of heart attacks. By preventing atherosclerosis (plaque buildup), it eases strain on the cardiovascular system and improves circulation.
The heart requires large amounts of energy to pump continuously, and CoQ10 is vital for producing ATP in heart muscle cells. This improves cardiac energy, efficiency, endurance, and recovery, especially in people with heart disease or fatigue. It also enhances nitric oxide availability, helping relax blood vessels, improve circulation, and lower blood pressure.
For those with congestive heart failure or taking statins (which can lower CoQ10 levels), supplementation can improve heart contractility, exercise tolerance, cardiovascular resistance, and overall cardiac performance. It may help prevent heart failure or support recovery after it occurs (5).
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The heart is not the only major organ supported by coenzyme Q10, as it also significantly boosts brain health. This is because the brain is highly vulnerable to free radical damage due to its high oxygen use and massive energy demands.
CoQ10’s antioxidant power shields neurons and brain lipids from oxidative stress, helping slow cognitive decline and age-related issues, including neurodegeneration. It also reduces microglial activation, the brain’s immune response, which lowers neuroinflammation that can contribute to memory loss and neurological degeneration.
CoQ10 supports mitochondrial ATP production in neurons and brain cells, enhancing brain energy and helping maintain focus, memory, and cognitive performance. It stabilises mitochondrial membranes, keeps them healthy, and prevents dysfunction. This is vital for preventing conditions like Alzheimer’s and Parkinson’s, where energy failure and oxidative damage play key roles.
By improving endothelial function and nitric oxide availability, CoQ10 boosts blood flow and nutrient delivery to brain tissue. Supporting mental clarity and alertness. It also protects the brain against damage from oxidative stress caused by medications, environmental toxins, or narcotics (6).
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Finally, coenzyme Q10 benefits both the skin and muscles. For the skin, it fuels the cells with ATP, helping them regenerate faster and maintain a healthy, youthful appearance. It also strengthens the skin barrier, allowing it to retain hydration, moisture, and softness.
Its antioxidant properties protect collagen and elastin from oxidative breakdown. Improving firmness, strength, and elasticity, and reducing fine lines and wrinkles (7). It also protects the skin from UV-induced free radicals, inflammation, pollution, and environmental damage. Reducing photoaging, dark spots, dullness, and redness, and promoting a smoother, younger-looking, more even complexion and skin tone.
Coenzyme Q10 drives ATP production in the muscle cells, improving energy, stamina, strength, endurance, and performance during physical activity. By improving mitochondrial efficiency, it helps muscles work longer before tiring, reducing or preventing exercise-induced fatigue.
Reducing oxidative stress and inflammation caused by intense exercise supports faster recovery and minimizes muscle damage and soreness. People taking statins should note that these medications lower natural Coenzyme Q10 levels, sometimes causing muscle weakness, pain, or cramps. CoQ10 supplementation helps restore balance and ease these symptoms (8).
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1] – https://pmc.ncbi.nlm.nih.gov/articles/PMC5557856/
2] – https://pubmed.ncbi.nlm.nih.gov/36091835/
3] – https://pubmed.ncbi.nlm.nih.gov/35958521/
4] – https://pubmed.ncbi.nlm.nih.gov/17914161/
5] – https://pubmed.ncbi.nlm.nih.gov/35348726/
6] – https://pubmed.ncbi.nlm.nih.gov/35908233/
7] – https://pubmed.ncbi.nlm.nih.gov/39148958/
8] – https://pmc.ncbi.nlm.nih.gov/articles/PMC9104583/
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