Betaine is a molecule found in beetroot, otherwise known as Trimethylglycine (TMG). It is currently being looked at for its many sporting benefits, but it is primarily known for its ability to significantly reduce homocysteine concentrations [1].

High homocysteine levels have been strongly linked to cardiovascular disease, so reducing them with betaine is a smart move for any man, but particularly older men.

Betaine is also effective at reducing liver inflammation and may help to prevent non-alcoholic fatty liver disease [2].

Anyone who is looking to reduce their risk of heart or liver disease can benefit from supplementing with betaine anhydrous.

This is an alternative form of vitamin B3 that is currently getting scientists very excited thanks to its anti-ageing properties. Its main function is to increase levels of nicotinamide adenine dinucleotide (NAD+).

Increasing NAD+ levels is thought to reduce your risk of chronic diseases such as heart disease, diabetes, and Alzheimer’s [3].

It can help to protect your brain cells, protect your heart, and it may even help with weight loss by increasing your metabolism [4].

Resveratrol is a naturally occurring phenol that can be found in certain plants. Famously, it is found in red wine. Trans-resveratrol is a version of resveratrol that is significantly easier for the body to absorb.

One of the main benefits of resveratrol is its ability to regulate blood sugar levels. Making it highly effective for dieting. This is why many studies have found small amounts of weight loss when it is taken [5].

Resveratrol can also help to lower cholesterol and it can lower inflammation by reducing C-reactive protein levels [6]. There is also evidence that it can lower oxidation, reduce blood pressure in people with high blood pressure levels, it may also improve memory and boost mood [7].

Like Nicotinamide and Betaine, Trans-resveratrol may help to protect the liver and the heart from disease.

 Berberine is found in many plants and tree bark, it has been used in Chinese and Indian medicine for centuries, but it is now getting attention from Western medicine due to its ability to aid people suffering from Type II diabetes.

There is evidence that Berberine can help to lower cholesterol levels, reduce blood glucose, and improve glycaemic control [8]. It may also be able to protect your heart and liver from harm.

ALA is an antioxidant that plays a crucial role in energy production. ALA is known to protect neurons in the brain, but it is increasingly being looked at for its ability to benefit people with type II diabetes. There is evidence that ALA may also help to boost male fertility. Its ability to reduce general oxidation should not be overlooked.

One of the first things to know about Quercetin is that it can increase the uptake of resveratrol in the body. But it is also an effective supplement in its own right. Helping to lower oxidative stress, reducing LDL (bad) cholesterol levels [9], and helping to lower the risk of leaky gut syndrome. Quercetin can be found in apples and onions, but not in the levels required to see results.

Hyaluronic acid (HA) is often used to treat joint pain and to reduce the appearance of fine lines and wrinkles on your skin. It also appears to work as an anti-inflammatory. Prime Male Life mostly uses HA to hydrate your skin and lubricate your joints.

There are many benefits to using collagen, but often collagen is derived from animal products. At Prime Male Life, we have used a vegan collagen blend in our formula, which provides amazing results and is vegan-friendly.

Collagen has many functions in the body, particularly as you age. Collagen supplementation has been found to reduce pain in people with arthritis. It also helps to lessen joint pain associated with exercise, or general mobility.

But one of its most important functions is to reduce signs of ageing in your skin. Supplementation can also help to delay the signs of ageing [10].

Fisetin is one of the most exciting supplement ingredients out there. It is currently being studied for its ability to treat numerous diseases, and it is known to be a highly effective antioxidant. Fisetin may also have nootropic benefits, allowing you to think clearer, and it may also lower inflammation [11].